Abdominal pregnancy presenting as a missed abortion at 16 weeks' gestation

ABSTRACT

Hong Kong Med J 2000;6:425-7 | Number 4, December 2000
CASE REPORT
Abdominal pregnancy presenting as a missed abortion at 16 weeks' gestation
KY Kun, PY Wong, MW Ho, CM Tai, TK Ng
Department of Obstetrics and Gynaecology, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong
 
 
We report on an abdominal pregnancy that presented as a missed abortion at 16 weeks' gestation and review the literature on the management of abdominal pregnancy. The clinical presentation of abdominal pregnancy varies, and the diagnosis depends on a high index of suspicion. Ultrasonography is useful for early diagnosis of the condition. The management depends on the gestation at presentation; for advanced abdominal pregnancy, surgical intervention is recommended. The treatment of the placenta is a matter of controversy. In general, expectant management is suggested. When the placenta is left behind, the use of prophylactic methrotrexate is not advocated. An awareness of abdominal pregnancy is very important for reducing associated morbidity and mortality.
 
Key words: Laparotomy; Pregnancy, abdominal/ultrasonography; Pregnancy complications; Pregnancy outcome
 
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Hypothyroidism presenting as hypercholesterolaemia and simvastatin-induced myositis

ABSTRACT

Hong Kong Med J 2000;6:423-4 | Number 4, December 2000
CASE REPORT
Hypothyroidism presenting as hypercholesterolaemia and simvastatin-induced myositis
YT Hung, VTF Yeung
Department of Medicine and Geriatrics, Our Lady of Maryknoll Hospital, 118 Shatin Pass Road, Wongtaisin, Hong Kong
 
 
We report on a 50-year-old woman who presented with hypertension. She was given simvastatin for hypercholesterolaemia. The creatine kinase level was 3180 U/L at the 3-month follow-up visit, which was thought to be due to simvastatin treatment. Although treatment was discontinued, the creatine kinase level 4 months later remained higher than 3000 U/L. Echocardiography revealed mild pericardial effusion and normal left ventricular function; the electromyogram was also normal. The patient subsequently showed signs and symptoms suggestive of hypothyroidism, which was confirmed by measurements of the concentration of thyroid-stimulating hormone (>100 mU/L) and free thyroxine (<2 pmol/L). Thyroxine replacement therapy normalised the creatine kinase and cholesterol levels. This case illustrates the importance of excluding underlying causes of hypercholesterolaemia before contemplating lipid-lowering therapy.
 
Key words: Hypercholesterolemia; Hypertension/complications; Hypothyroidism; Lipids/blood; Myositis/chemically induced
 
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A case of giant malignant phaeochromocytoma

ABSTRACT

Hong Kong Med J 2000;6:325-8 | Number 3, September 2000
CASE REPORT
A case of giant malignant phaeochromocytoma
FKW Chan, KL Choi, SC Tiu, CC Shek, TK Au Yong
Department of Medicine, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
 
 
Malignant phaeochromocytoma is defined as the presence of tumour deposits at sites that are normally devoid of chromaffin cells. We report on a 63-year-old man who had a giant malignant phaeochromocytoma of the right adrenal gland that encased the inferior vena cava. The urinary excretion rates of catecholamines and their metabolites were normal, except for normetanephrine, which was excreted at a higher rate than normal. The tumour was surgically unresectable by laparotomy. Postoperatively, the patient was given a 4-month trial of subcutaneous octreotide and intravenous meta-iodobenzylguanidine I 131. Occult lung secondary tumours were first detected by meta-iodobenzylguanidine scintigraphy after 2 years, and the patient died of bone and lung metastases 1 year later. Because phaeochromocytoma is rare, local experience in managing this disease is limited. This report alerts physicians of the methods of diagnosing and managing surgically unresectable malignant phaeochromocytoma.
 
Key words: Adrenal gland neoplasms; Iodine radioisotopes; 3-Iodobenzylguanidine; Octreotide; Phaeochromocytoma
 
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Acute epiglottitis presenting as the sensation of a foreign body in the throat

ABSTRACT

Hong Kong Med J 2000;6:322-4 | Number 3, September 2000
CASE REPORT
Acute epiglottitis presenting as the sensation of a foreign body in the throat
CH Chung
Accident and Emergency Department, North District Hospital, Sheung Shui, New Territories, Hong Kong
 
 
A 49-year-old man presented with dysphagia and the sensation of a foreign body in the throat, after he had swallowed chicken meat that contained bones during the previous evening. There were no respiratory symptoms. A plain lateral soft-tissue X-ray of the neck and oesophagogastroduodenoscopy showed a grossly swollen epiglottis. His condition improved rapidly with intravenous antibiotic therapy. As acute epiglottitis may be a sudden life-threatening condition, a high index of suspicion should be maintained for patients who present with an obstructive sensation in the throat.
 
Key words: Acute disease; Adult; Epiglottitis/radiography; Foreign bodies; Pharynx
 
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Removal of a dinner fork from the stomach by double-snare endoscopic extraction

ABSTRACT

Hong Kong Med J 2000;6:319-21 | Number 3, September 2000
CASE REPORT
Removal of a dinner fork from the stomach by double-snare endoscopic extraction
PTL Yong, CH Teh, M Look, SB Wee, JCH Tan, SP Chew, CH Low
Grace Polyclinic, 134 East Coast Road, Singapore 428819, Singapore
 
 
Long and pointed foreign objects in the stomach are difficult to remove by endoscopy, and they can cause complications such as perforation and impaction. The endoscopic removal of long and pointed objects involves the following principles: (1) presenting the blunt end cephalad to prevent perforation or impaction during extraction; (2) orienting the long axis of the object in the line of extraction; and (3) applying traction to the foreign body without losing grip. Currently practised methods of extraction, which use a protector hood or an overtube, do not address these three principles. We report on a case in which an ingested metal dinner fork was removed from the stomach by using a double wire-loop snare technique. This method uses two snares to hold the object and allows the endoscopist to change the presentation, orient the axis, and maintain traction to allow the safe removal of long and pointed objects.
 
Key words: Endoscopy, gastrointestinal; Foreign bodies/therapy; Gastroscopy/methods; Stomach
 
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Management of thallium poisoning

ABSTRACT

Hong Kong Med J 2000;6:316-8 | Number 3, September 2000
CASE REPORT
Management of thallium poisoning
PWI Pau
Suite 202, 175 N. Jackson Avenue, San Jose, California, CA 95116, United States
 
 
A case of acute thallium poisoning in a 67-year-old Chinese woman is described. She presented with acute pain in the chest, abdomen, and lower limbs. The diagnosis was not made, however, until alopecia developed. Detoxification treatment, which included Prussian blue (potassium ferric hexacyanoferrate) was then given, but further neurological damage occurred. The patient's motor function recovered after 1 year, but residual sensory neuropathy remained. This case illustrates that tissue-bound thallium may cause prolonged neurological damage if detoxification therapy is not commenced within 72 hours of the onset of acute poisoning. Acute abdominal pain and painful neuropathy in the lower extremities are important early diagnostic clues for timely therapy. However, by the time alopecia develops--typically around 2 weeks after the onset of symptoms--detoxification therapy may not be able to prevent the development of prolonged neurological damage.
 
Key words: Ferrocyanides/therapeutic use; Poisoning/drug therapy; Thallium/poisoning; Time factors
 
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A case of Penicillium marneffei osteomyelitis involving the axial skeleton

ABSTRACT

Hong Kong Med J 2000;6:231-3 | Number 2, June 2000
CASE REPORT
A case of Penicillium marneffei osteomyelitis involving the axial skeleton
TS Pun, D Fang
Department of Orthopaedics and Traumatology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
 
 
Fungal infection of bone by Penicillium marneffei is rare. We report on a case of Penicillium marneffei infection in a Filipino woman, which involved multiple soft-tissue abscesses and infection of the axial skeleton. Early diagnosis and treatment of this potentially reversible disease is emphasised. Such an approach is essential to prevent bony destruction from becoming too advanced and, more importantly, to prevent any damage to the spinal cord from occurring.
 
Key words: Antifungal agents; Bone diseases/etiology; Bone diseases/radiology; Osteomyelitis; Penicillium
 
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Three different presentations of bulimia nervosa

ABSTRACT

Hong Kong Med J 2000;6:227-30 | Number 2, June 2000
CASE REPORT
Three different presentations of bulimia nervosa
M Lam, S Lee
Department of Psychiatry, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
 
 
This case report describes the different presentations of three women with bulimia nervosa, all of whom demonstrated purging behaviour. Two of the patients also had hypokalaemia, whereas the third exhibited Russell's sign--that is, calluses on the dorsum of each hand. Drug treatment and psychosocial intervention improved the condition of all three patients. The report emphasises the need for both health care professionals and the public to recognise this potentially dangerous but treatable disorder.
 
Key words: Body mass index; Bulimia/diagnosis; Female; Hypokalemia; Vomiting/etiology
 
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Facial nerve palsy and Kawasaki disease

ABSTRACT

Hong Kong Med J 2000;6:224-6 | Number 2, June 2000
CASE REPORT
Facial nerve palsy and Kawasaki disease
LKH Poon, KS Lun, YM Ng
Department of Paediatrics, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
 
 
We report on a case of facial nerve palsy associated with Kawasaki disease in a 2-year-old boy. Facial nerve palsy is one of the rare neurological manifestations of Kawasaki disease. Twenty-seven other cases that have been reported in the literature are reviewed. There is a high incidence of coronary artery aneurysm (52%) and a female predilection in patients with Kawasaki disease. The facial palsy associated with the disease is self-limiting. Recovery is spontaneous in surviving patients, although the use of intravenous immunoglobulin may be able to hasten the recovery.
 
Key words: Facial nerve diseases; Facial paralysis; Immunoglobulins, intravenous/therapeutic use; Mucocutaneous lymph node syndrome/complications
 
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Interferon treatment for multiple sclerosis patients in Hong Kong

ABSTRACT

Hong Kong Med J 2000;6:221-3 | Number 2, June 2000
CASE REPORT
Interferon treatment for multiple sclerosis patients in Hong Kong
KK Lau, PO Lee, KY Chan, YW Chan, KF Chin
Department of Medicine, Princess Margaret Hospital, Kwai Chung, Hong Kong
 
 
We report on nine patients with multiple sclerosis who had received interferon beta-1a treatment for 6 months or more. Seven patients were Chinese and two were Caucasian. Seven patients had the relapsing-remitting type of multiple sclerosis, one had the primary-progressive type, and one had the progressive-relapsing type. Among the six compliant patients with the relapsing-remitting type of disease, four had less frequent relapses after treatment. This study could not show whether or not the use of interferon beta-1a was beneficial to non-compliant patients, or patients with other types of multiple sclerosis.
 
Key words: Interferon-beta/therapeutic use; Multiple sclerosis/drug therapy; Treatment outcome
 
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