A case of oral myiasis due to Chrysomya bezziana

ABSTRACT

Hong Kong Med J 2003;9:454-6 | Number 6, December 2003
CASE REPORT
A case of oral myiasis due to Chrysomya bezziana
KHL Ng, KT Yip, CH Choi, KH Yeung, TW Auyeung, ACC Tsang, L Chow, TL Que
Department of Clinical Pathology, Tuen Mun Hospital, Tsing Chung Koon Road, Tuen Mun, Hong Kong
 
 
Chrysomya bezziana is a causative agent of obligatory myiasis. We report the first case of human infestation of Chrysomya bezziana in Hong Kong in an 89-year-old woman who had previously had a stroke. One day after hospital admission for fever, a small fissure at the labial gingiva of the upper incisors and several ulcerative lesions at the hard palate were noticed during routine mouth care. A live maggot was seen protruding from the small fissure. In the following few days, a total of seven maggots were removed by forceps. Urgent computed tomography and magnetic resonance imaging of the oral cavity showed an ulcerative soft-tissue lesion over the anterior palate, with a fistula communicating to the labial gingiva. The tissue loss was limited to the bony margin of the hard palate. The infestation was managed by manual removal of maggots and surgical debridement. Medical personnel taking care of old or debilitated patients need to bear in mind the possibility of Chrysomya bezziana infestation to be able to make a prompt diagnosis and implement relevant intervention to prevent extensive tissue destruction.
 
Key words: Chrysomya bezziana; Hong Kong; Myiasis
 
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Acute-on-chronic subdural haematoma: a rare complication after spinal anaesthesia

ABSTRACT

Hong Kong Med J 2003;9:384-6 | Number 5, October 2003
CASE REPORT
Acute-on-chronic subdural haematoma: a rare complication after spinal anaesthesia
ST Tan, CT Hung
Department of Anaesthesiology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
 
 
An 88-year-old woman with an undiagnosed chronic subdural haematoma underwent emergency repair of a femora hernia under spinal anaesthesia. The patient complained of headache postoperatively, and a subsequent computed tomography brain scan showed an acute-on-chronic subdural haematoma, with midline shift and impending coning. The patient recovered completely after surgical decompression. The difficulty in diagnosing chronic subdural haematoma in the elderly patient with no history of trauma is discussed, along with the differential diagnosis of headache following spinal anaesthetic in this age-group.
 
Key words: Acute subdural hematoma; Aged, 80 and over; Anethesia, spinal
 
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A case of partial trisomy 13 presenting with hyperinsulinaemic hypoglycaemia

ABSTRACT

Hong Kong Med J 2003;9:381-3 | Number 5, October 2003
CASE REPORT
A case of partial trisomy 13 presenting with hyperinsulinaemic hypoglycaemia
YK Shiu, FM Lo, TS Lam, CB Chow
Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Laichikok, Hong Kong
 
 
We report on a newborn baby with partial trisomy 13 who presented with multiple dysmorphic features and hyperinsulinaemic hypoglycaemia. Cytogenetic study on peripheral blood lymphocytes showed 47,XY,+mar in all cells analysed; fluorescent in situ hybridisation showed that the marker was solely derived from chromosome 13. The final karyotype was 47,XY,+del(13)(q14q32). Milk formula through a nasogastric drip and intravenous glucose infusion were given to prevent further hypoglycaemia. However, the baby developed occasional episodes of hypoglycaemia during bolus feeding. Hence, diazoxide was given, at a dosage of 10 mg/kg per day from day 24. Thereafter, no hypoglycaemic episodes were detected. Subsequent follow-up revealed satisfactory growth, global developmental delay, and left divergent squint.
 
Key words: Hyperinsulinism; Hypoglycemia; Trisomy
 
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Cholestatic jaundice caused by sequential carbimazole and propylthiouracil treatment for thyrotoxicosis

ABSTRACT

Hong Kong Med J 2003;9:377-80 | Number 5, October 2003
CASE REPORT
Cholestatic jaundice caused by sequential carbimazole and propylthiouracil treatment for thyrotoxicosis
AOO Chan, IOL Ng, CM Lam, TWH Shek, CL Lai
Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
 
 
A 36-year-old Chinese man presented to the Queen Mary Hospital in August 1999 with a 2-week history of jaundice due to propylthiouracil treatment for thyrotoxicosis. He had previously received carbimazole but had developed an urticarial skin rash after 2 weeks of treatment. The patient developed liver failure and fulminant pneumonitis shortly after hospital admission. Despite receiving treatment with broad-spectrum antibiotics and intravenous immunoglobulin, he died 11 days after the onset of the respiratory symptoms. Postmortem examination using electron microscopy showed typical glycogen bodies within the cytoplasm of the hepatocytes, which corresponded to eosinophilic cytoplasmic inclusion bodies visible under light microscopy. Immunohistochemical studies of the inclusion bodies were positive for carcinoembryonic antigen and albumin, and negative for fibrinogen, complement protein C3, immunoglobulins G, M, and A, alpha-fetoprotein, and alpha-1-antitrypsin. This is the first report of a patient who received two sequential antithyroid drugs and developed predominate cholestasis with unique histological features. Extreme caution should be taken when a patient develops allergy to one type of antithyroid drug, because cross reactivity may develop to the other type.
 
Key words: Antithyroid agents; Carbimazole; Cholestasis; Propylthiouracil
 
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Cholangiocarcinoma presenting as pseudoachalasia and gastroparesis

ABSTRACT

Hong Kong Med J 2003;9:296-8 | Number 4, August 2003
CASE REPORT
Cholangiocarcinoma presenting as pseudoachalasia and gastroparesis
VKS Leung, PS Kan, MS Lai
Department of Medicine and Geriatrics, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong
 
 
Cholangiocarcinoma most commonly presents as painless progressive jaundice. We report a case occurring in a 56-year-old Chinese woman with an unusual presentation of progressive dysphagia and vomiting. Oesophageal manometric and barium studies were indicative of achalasia, and computed tomography confirmed the presence of cholangiocarcinoma extending to the gastroesophageal junction and proximal lesser curve of the stomach. In this case, a constricting tumour at the gastroesophageal junction with probable invasion of the vagus nerves led to features of achalasia and gastroparesis.
 
Key words: Cholangiocarcinoma; Esophageal achalasia; Gastroparesis
 
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Use of botulinum toxin type A in a case of persistent parotid sialocele

ABSTRACT

Hong Kong Med J 2003;9:293-4 | Number 4, August 2003
CASE REPORT
Use of botulinum toxin type A in a case of persistent parotid sialocele
TL Chow, SPY Kwok
Division of Head and Neck, Breast and Reconstructive Surgery, Department of Surgery, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong
 
 
Sialocele is an uncommon complication of parotidectomy. Most cases resolve after conservative therapy consisting of repeated aspiration and pressure dressing. The condition is, however, occasionally resistant to such therapy. We report on a 52-year-old Chinese man who had a 10-year history of right parotid swelling. Following fine-needle aspiration cytology, Warthin’s tumour was diagnosed, but after elective parotidectomy, a swelling developed and parotid sialocele was diagnosed. Botulinum toxin type A was given after the sialocele had persisted for almost 3 weeks after surgery, and after conservative management had been tried; the sialocele disappeared after two doses of treatment. Botulinum toxin therapy was thus an effective method of treating persistent sialocele.
 
Key words: Botulinum toxins; Cysts; Parotid diseases
 
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Subtle perforation of the oesophagus by a foreign body

ABSTRACT

Hong Kong Med J 2003;9:290-2 | Number 4, August 2003
CASE REPORT
Subtle perforation of the oesophagus by a foreign body
CH Chung
Accident and Emergency Department, North District Hospital, 9 Po Kin Road, Sheung Shui, Hong Kong
 
 
A case of subtle oesophageal perforation caused by a foreign body is described. A 48-year-old woman had had a chicken bone impacted in the upper oesophagus for 4 days. At presentation, the bone was dislodged at endoscopy, and two small round depressions at opposite sides of the oesophageal wall were visible. The chest X-ray findings were normal. Computed tomography of the thorax detected a small amount of air in the mediastinum. The water-soluble contrast swallow test showed no evidence of leakage. The patient was successfully treated using conservative measures.
 
Key words: Esophageal perforation; Esophagoscopy; Foreign bodies; Mediastinal emphysema
 
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Ruptured phaeochromocytoma—a lesson in acute abdomen

ABSTRACT

Hong Kong Med J 2003;9:221-3 | Number 3, June 2003
CASE REPORT
Ruptured phaeochromocytoma—a lesson in acute abdomen
MKY Chan, HW Tse, FPT Mok
Department of Surgery, Caritas Medical Centre, 111 Wing Hong Street, Shamshuipo, Hong Kong
 
 
Phaeochromocytoma may present as acute abdomen. This report is of a patient with spontaneous rupture of phaeochromocytoma who presented with abdominal pain and a tender abdominal mass. Ruptured phaeochromocytoma is a rare surgical emergency, with only 30 cases reported in the literature. The classical clinical triad of signs is intense vasoconstriction, tachycardia, and labile blood pressure. Computed tomography scanning of
 
Key words: Abdomen, acute; Pheochromocytoma
 
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Kennedy’s disease

ABSTRACT

Hong Kong Med J 2003;9:217-20 | Number 3, June 2003
CASE REPORT
Kennedy’s disease
KM Au, KK Lau, AYW Chan, B Sheng, HL Li
Department of Pathology, Princess Margaret Hospital, Princess Margaret Hospital Road, Laichikok, Hong Kong
 
 
Kennedy’s disease is an X-linked, neurodegenerative disorder, characterised by lower motor neuron syndrome. This report gives the clinical details of six male patients with Kennedy’s disease diagnosed at Princess Margaret Hospital. Three were initially diagnosed with other neurological diseases, with the diagnosis of Kennedy’s disease made after genetic testing. This hereditary disease should be considered in male patients with muscle weakness, particularly those with a presentation suggesting atypical motor neuron disease.
 
Key words: Genetic diseases, X-linked; Motor neuron disease; Muscular atrophy, spinal; Receptors, androgens
 
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Unimuscular neuromuscular insult of the leg in partial anterior compartment syndrome in a patient with combined fractures

ABSTRACT

Hong Kong Med J 2003;9:214-6 | Number 3, June 2003
CASE REPORT
Unimuscular neuromuscular insult of the leg in partial anterior compartment syndrome in a patient with combined fractures
YF Leung, SPS Ip, OM Chung, YL Wai
Department of Orthopaedics and Traumatology, Yan Chai Hospital, Tsuen Wan, Hong Kong
 
 
A complicated case of ipsilateral fractures of the left femur and tibia after a road traffic accident is reported. The patient presented with numbness of the first web of his left foot and contracture of the extensor hallucis longus muscle, with fixed length deformity after intramedullary nailing of the femur and tibia. The extensor digitorum longus and tibialis anterior muscles were spared. Tinel’s sign could be elicited at the mid-portion of the anterior compartment of the injured leg. This indicated that the distal half of the anterior tibial nerve (deep peroneal nerve), together with the extensor hallucis muscle of the anterior compartment of the leg, had been damaged. The subsequent management of this patient is described.
 
Key words: Femur; Fractures; Tibia
 
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