Prevalence of neuronal membrane target antibodies in first-episode psychosis: abridged secondary publication
CSY Chong1, WTL Lo1, CM Mak2, SPL Chen2, KK Lau3, B Sheng3
1 Department of Psychiatry, Kwai Chung Hospital
2 Department of Pathology, Princess Margaret Hospital
3 Department of Medicine and Geriatrics, Princess Margaret Hospital
1. Psychosis related to anti-N-methyl-D-aspartate (NMDA) antibodies is uncommon in Hong Kong, with a prevalence of 1.5%.
2. It is clinically difficult to differentiate first-episode psychotic patients with or without anti-NMDA antibodies.
3. A high index of suspicion of psychosis related to anti-NMDA antibodies is needed for cases with unexplained abnormal electroencephalography findings.
4. Future studies may include only patients presenting as schizophrenia, owing to a potentially higher yield.