Gastrodia-Uncaria water extract and tissue plasminogen activator for treating embolus-induced cerebral ischaemia: abridged secondary publication
JW Xian1, AYT Choi1, WN Leung1, L Li2, CBS Lau1, TWH Leung3, CW Chan1
1School of Chinese Medicine, The Chinese University of Hong Kong
2Department of Chemistry, University of Alberta
3Department of Medicine and Therapeutics, The Chinese University of Hong Kong
1. The treatment potential of Gastrodia-Uncaria water extract on cerebral ischaemia was demonstrated in terms of reduction of brain infarct volume of the brain, improvement of the motor behaviour recovery, stimulation of anti-oxidative enzyme, inhibition of matrix metalloproteinase, induction of neurotrophins, and maintenance of brain tissue integrity.
2. Intravascular administration of tissue plasminogen activator is well tolerated with oral administration of Gastrodia-Uncaria water extract, which may reduce the risk of tissue plasminogen activator–induced intracranial haemorrhage.