MicroRNA and its link to osteoblasts in adolescent idiopathic scoliosis: abridged secondary publication
JCY Cheng, A Moreau, WYW Lee, TP Lam, BHK Yip, RKW Choy
Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong
1. Plasma miR-96 and miR-224 levels significantly increased in those with adolescent idiopathic scoliosis (AIS), compared with controls.
2. Plasma miR-96 and miR-224 correlated with bone quality parameters and bone turnover markers in AIS.
3. Aberrant level of miR-96 and miR-224 may contribute to abnormal osteoblast activities in AIS.