Transfer of HIV-1 from HIV-1 latently infected CD34+ haematopoietic progenitors to CD4+ T cells
AKL Cheung, Y Huang, M Chen, ZW Chen
AIDS Institute, Department of Microbiology, LKS Faculty of Medicine, The University of Hong Kong
1. HIV-1 can infect CD34+ progenitor stem cells and become latent.
2. Latent HIV-1 can affect the CD34 cell to halt homeostasis.
3. HIV-1–infected CD34+ progenitors may be a vehicle for viral dissemination.