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Triiodothyronine augmentation for the treatment
of depression in substance misusers unresponsive to tricyclic antidepressants
CK Kan, TP Ho
Department of Psychiatry, Queen Mary Hospital, 102 Pokfulam Road,
Hong Kong
We report on two substance misusers with depression
resistant to tricyclic antidepressant treatment who responded to
triiodothyronine augmentation. The management of resistant depression,
augmentation strategies with particular reference to triiodothyronine,
and the possible mechanism of action of triiodothyronine are discussed.
Hong Kong Med J 2001;7:299-302
Key words: Antidepressive agents, tricyclic; Depression;
Triiodothyronine, drug effects; Triiodothyronine, therapeutic use
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