Hong Kong Med J 2012;18:156-9 | Number 2, April 2012
Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax
Viola KT Leung, Stephen SH Suen, YH Ting, LW Law, TK Lau, TY Leung
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
Chylothorax is a rare congenital condition associated with significant perinatal mortality and morbidity. Previous treatments with repeated thoracocentesis or thoracoamniotic shunting were technically demanding, and associated with significant procedure-related complications and neonatal complications. Here we report the first successful case in Hong Kong treated by a simple and effective intervention, namely pleurodesis with OK-432, in a fetus presenting at 20 weeks of gestation with bilateral pleural effusion.
Key words: Chylothorax; Picibanil; Pleural effusion
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