Hong Kong Med J 2009;15:359-64 | Number 5, October 2009
Use of Onyx (a patented ethylene-vinyl alcohol copolymer formulation) embolisation of cerebral arteriovenous malformations in Hong Kong: initial experience
George KC Wong, Simon CH Yu, XL Zhu, Michael KM Kam, WS Poon
Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
OBJECTIVE. To review the experience with Onyx embolisation of cerebral arteriovenous malformation.
DESIGN. Prospective study.
SETTING. A regional neurosurgical centre in Hong Kong.
PATIENTS. Data of patients with cerebral arteriovenous malformation who underwent Onyx embolisation over a 14-month period were prospectively collected.
RESULTS. Eleven sessions of Onyx embolisation were performed in nine patients with cerebral arteriovenous malformations, seven of which had ruptured. Total occlusion was achieved in three (33%) of the patients, and subtotal occlusion (over 80% occlusion) in three out of four with Spetzler-Martin grade-III/IV malformations. One patient developed mild permanent neurological deficit.
CONCLUSION. Onyx embolisation of cerebral arteriovenous malformations is feasible in Hong Kong. Careful patient and target selection are important.
Key words: Embolization, therapeutic; Intracranial arteriovenous malformations; Polyvinyls; Treatment outcome
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