Hong Kong Med J 2009;15:288-90 | Number 4, August 2009
Primary hepatic peripheral T-cell lymphoma in a patient with chronic hepatitis B infection
Vincent KS Leung, SY Lin, Tony KL Loke, TN Chau, CY Leung, TP Fung, SH Lam
Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong
We report a case of primary hepatic peripheral T-cell lymphoma in a patient with hepatitis B virus-related cirrhosis. This patient presented with a solitary hepatic lesion with computed tomography and magnetic resonance imaging features that did not resemble hepatocellular carcinoma. Subsequent biopsy of the lesion revealed that it was a peripheral T-cell lymphoma. The patient was successfully treated with multi-agent chemotherapy followed by radiofrequency ablation. Although hepatocellular carcinoma is the most frequently encountered primary hepatic tumour in patients with hepatitis B virus-related cirrhosis, primary hepatic lymphoma should also be borne in mind. Nevertheless, primary hepatic lymphoma is a rare entity, and has no proven association with chronic hepatitis B infection.
Key words: Carcinoma, hepatocellular; Hepatitis B; Liver cirrhosis; Lymphoma
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