Hong Kong Med J 2025;31(Suppl 7):S32-5
Diagnostic accuracy of gingival bleeding on brushing, salivary activated MMP-8 and a self-reported questionnaire in early detection of periodontitis: abridged secondary publication
LJ Jin1, G Pelekos1, DKL Ho1, M Tonetti1,2
1 Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China
2 Shanghai Jiao Tong University School of Medicine, College of Stomatology; National Center of Stomatology; and National Clinical Research Center of Oral Diseases, Shanghai, China
 
 
  1. The modified questionnaire of the Centers for Disease Control and Prevention and the American Academy of Periodontology is useful for self-detecting periodontal diseases, and its integration with demographic/lifestyle variables further improves diagnostic performance.
  2. The oral rinse activated MMP-8 point-of-care test can identify different severities of periodontitis, and combining it with individual and lifestyle profiles enhances diagnostic performance.
  3. Self-reported gingival bleeding on brushing is a sign of periodontal diseases, particularly gingival inflammation.
  4. The haemoglobin levels of saliva/toothpaste slurry could be useful for identifying generalised severe periodontitis.
  5. Salivary biomarkers of certain adipose metabolism–related and ageing-related proteins as well as inflammatory cytokines may potentially identify patients with severe periodontitis.