Risk of intracerebral haemorrhage in patients with cerebral microbleeds taking warfarin for atrial fibrillation: a prospective study
YO Soo1, J Abrigo2, W Chu2, KT Leung1, WC Fong3, SH Li4, R Li5, PW Ng6, KK Wong7, LKS Wong1, TWH Leung1
1 Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong
2 Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong
3 Department of Medicine, Queen Elizabeth Hospital
4 Department of Medicine, North District Hospital
5 Department of Medicine, Pamela Youde Nethersole Eastern Hospital
6 Department of Medicine and Geriatrics, United Christian Hospital
7 Department of Medicine, Yan Chai Hospital
 
 
1. In Chinese patients with atrial fibrillation, the presence of ≥5 cerebral microbleeds on magnetic resonance imaging is associated with an increased risk of warfarin-related intracerebral haemorrhage.
2. Evaluation of cerebral microbleeds in patients with atrial fibrillation may help identify patients at higher risk of warfarin-related intracerebral haemorrhage, who may benefit from alternative treatment options with lower bleeding risk.