Hong Kong Med J 2014;20(Suppl 6):S39-43
Cervical cancer screening by enhanced cytology: application of novel markers
ANY Cheung, XY Guan, HYS Ngan
Department of Pathology, Queen Mary Hospital, The University of Hong Kong
1. p634A4, TAp73, and DJ-1 immunocytochemistry as well as in situ hybridisation for the OSMR1, PAPD7/POLS, PRAKK1, and TRIO genes helped to identify cervical carcinoma and high-grade precursor cells.
2. p634A4 immunoreactivity is a potential marker for triage of atypical squamous cells of undetermined significance.
3. TAp73 immunoreactivity is a potential marker for triage of low-grade squamous intraepithelial lesions.
2. p634A4 immunoreactivity is a potential marker for triage of atypical squamous cells of undetermined significance.
3. TAp73 immunoreactivity is a potential marker for triage of low-grade squamous intraepithelial lesions.