Hong Kong Med J 2013;19:362–4 | Number 4, August 2013
Early consideration of anti-NMDAR encephalitis in unexplained encephalopathy
Maggie LY Yau, Eva LW Fung
Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong
With the identification of anti-NMDAR (N-methyl-D-aspartate receptor) antibody, the spectrum of anti-NMDAR encephalitis has been expanding. The condition is also increasingly recognised in children, though younger patients are less likely to have tumours, while behavioural and speech problems, seizures, and abnormal movements are common early presenting features. Here we present yet another case with subtle, non-specific clinical symptoms that responded promptly to intravenous immunoglobulin. We believe this illustrates the importance of considering this uncommon differential diagnosis in the management of unexplained neurological conditions.
Key words: Antibodies; Diagnosis; Encephalitis
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