Hong Kong Med J 2012;18(Suppl 3):S35-8
Characterisation of animal angiotensin- converting enzyme 2 receptors and use of pseudotyped virus to correlate receptor binding with susceptibility of SARS-CoV infection
KKB Li, CW Yip, CC Hon, CY Lam, F Zeng, FCC Leung
School of Biological Sciences, The University of Hong Kong, Hong Kong
1. Comprehensive surveillance of civets, mice, cats, Golden Syrian hamsters, and horseshoe bats is suggested when SARS or SARS-like CoVs re-emerge in the human population in the future.
2. Rabbits and horseshoe bats are animal carriers of SARS-CoV.
3. Investigation of the genetic diversity of CoV in two bat species (Rhinolophus sinicus and Rhinolophus pearsonii) should provide insights into the direct ancestor of human SARS-CoV.