Hong Kong Med J 2012;18(Suppl 2):S42-4
Neuroprotective effects of minocycline on double-stranded RNA- induced neurotoxicity in cultured cortical neurons
SY Yik, MS Yu, YS Ho, CSW Lai, YT Cheung, KF So, RCC Chang
Laboratory of Neurodegenerative Diseases, Department of Anatomy, Research Centre of Heart, Brain, Hormone and Healthy Aging, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong
1. Minocycline, memantine, and glycoconjugate were assessed for their ability to protect cultured primary cortical neurons against double-stranded RNA-induced neurotoxicity.
2. Minocycline but not memantine or glycoconjugate protected cultured cells and warrants further investigation.