Hong Kong Med J 2011;17(Suppl 6):S41-3
Risk of liver cancer in patients with hepatitis B or C
JQ Huang, GF Zheng, CL Lai, MF Yuen, BCY Wong
Clinical Trials Centre, Faculty of Medicine, The University of Hong Kong, Hong Kong
1. Among hepatitis B virus carriers, infection with genotype C significantly increases the risk of developing hepatocellular cancer compared to those without this genotype.
2. Among hepatitis C virus carriers, infection with genotype 1b increases the risk of hepatocellular cancer two-fold compared to controls without this genotype.
3. Such increased risk should be explained as risk over and above the existing risk associated with each infection.
4. Hepatitis C virus genotypes 1a and 2a are associated with decreased risk of hepatocellular cancer.