Hong Kong Med J 2010;16:489-92 | Number 6, December 2010
Cast nephropathy with acute renal failure treated with high cut-off haemodialysis in a patient with multiple myeloma
HP Shum, KC Chan, CC Chow, Bonnie CS Kho, WW Yan
Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong
We report a case of a Chinese woman who presented with multiple myeloma and acute renal failure due to cast nephropathy, with an extremely high serum lambda free light chain concentration. She was successfully treated with chemotherapy and high cut-off extended haemodialysis. High cut-off haemodialysis is a new treatment modality which can achieve rapid free light chain clearance. This may contribute to a better renal outcome and overall prognosis for patients with multiple myeloma.
Key words: Kidney failure, acute; Multiple myeloma; Plasma exchange; Renal dialysis
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