Hong Kong Med J 2010;16(Suppl 4):S45-6
A multilocus sequence typing system for Penicillium marneffei: an international molecular cyber system for tracking its origin and transmission
KY Yuen, PCY Woo, SKP Lau
Department of Microbiology, The University of Hong Kong, Hong Kong
1. A multilocus sequence typing (MLST) system was developed for Penicillium marneffei, an emerging opportunistic infection in Southeast Asia.
2. A website for P marneffei MLST is available at http://mlstdb.hku. hk:14206/MLST_index.html to enable comparison of strains from different localities.
3. Our P marneffei MLST system appears to be more discriminating and more suitable for epidemiology studies than other similar systems.
4. Non-housekeeping genes should be incorporated into the MLST system to achieve greater discriminatory power.