Hong Kong Med J 2010;16(Suppl 4):S4-7
Establishment of public norovirus genome database in Hong Kong
WK Leung, HLY Chan, JJY Sung
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
1. Phylogenetic analysis demonstrated that a panel of genetically diverse human norovirus (hNoV) strains are circulating in Hong Kong; those belonging to the GII.4 cluster appear to be most prevalent.
2. NoroBase is a publicly accessible web-based hNoV database and provides complete viral genomic and partial gene sequences to facilitate local studies.
3. With the annotated sequences in NoroBase, virus genotyping via homology search against our database provides an efficient way for epidemiologists and public health professionals to study epidemiologic patterns of local hNoV infections and identify and characterise aetiologic agents during gastroenteritis outbreaks.