Hong Kong Med J 2010;16:223-6 | Number 3, June 2010
Bacille Calmette-Guerin osteomyelitis of the proximal femur
PK Chan, Bobby KW Ng, CY Wong
Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Shatin, Hong Kong
All newborns in Hong Kong are given bacille Calmette-Guerin vaccinations. Reported complications include formation of regional and extra-regional localised abscesses, osteomyelitis, and lymphadenitis. Several cases of bacille Calmette-Guerin osteomyelitis have been reported in Europe, but there are few reports of this in Asia. To the author's knowledge, this is the first case report of bacille Calmette-Guerin osteomyelitis in Hong Kong. Bacille Calmette-Guerin osteomyelitis, although rare, should be kept in mind as a potential complication of bacille Calmette-Guerin vaccination. Clinical suspicion, early diagnosis using an image-guided tissue biopsy and polymerase chain reaction study, and early commencement of chemotherapy are key to the effective management of this problem.
Key words: Abscess; BCG vaccine; Femur; Mycobacterium bovis; Osteomyelitis
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