Hong Kong Med J 2009;15(Suppl 2):S43-6
Association of cytokine and chemokine gene polymorphisms with severe acute respiratory syndrome
YL Lau, JSM Peiris
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
1. The IFN-γ +874A allele and RANTES -28 G allele are risk factors for SARS susceptibility.
2. The RANTES -28 G allele plays a role in the pathogenesis of SARS.
3. The polymorphisms of IL-10, TNF-_, IL-12, IP-10, Mig and MCP-1 are not associated with SARS susceptibility.