Hong Kong Med J 2006;12:319-21 | Number 4, August 2006
Oncogenic osteomalacia associated with an occult phosphaturic mesenchymal tumour: clinico-radiologico-pathological correlation and ultrastructural studies
FMF Cheung, L Ma, WC Wu, TH Siu, PT Choi, YP Tai
Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong
A middle-aged man presented with bone pain at multiple sites due to tumour-induced osteomalacia. The underlying occult phosphaturic mesenchymal tumour was identified by octreotide scan 5 years after presentation and confirmed by computed tomography. Tumour resection resulted in normalisation of blood chemistry and bone densitometry. Clinico-radiologico-pathological correlation and ultrastructural studies of the tumour threw light on the pathogenesis and pathophysiology of this rare disease.
Key words: Fibroblast growth factors; Osteomalacia; Soft tissue neoplasms
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