Search HKMJ:

 

To download the Chinese version of the issue digest, please click here. You may find the links to download the full version of these articles on the issue table of content page.

 
Hong Kong Medical Journal June 2004 Issue Digests
 
UNRELATED UMBILICAL CORD BLOOD TRANSPLANATION IN CHILDREN:
THE OUTCOME IS COMPARABLE TO BONE MARROW TRANSPLANTATION

Hong Kong Med J 2004;10:89-95

The Hong Kong Red Cross Blood Transfusion Service Cord Blood Bank (HKRCBTS) stores cord blood units of good quality for transplantation, the outcome of which was comparable to that of bone marrow transplantation. 9 units of transplantation have been provided by HKRCBTS from 1999 to 2003, of which 8 units were sent to the Prince of Wales Hospital. A review of 8 cases was published in the April 2004 issue of Hong Kong Medical Journal.

Researchers reported that all 8 patients, aged from 12 months to 9.4 years at the time of transplantation, achieved neutrophil engraftment at a median time of 13 days. They all showed production of blood cells of complete donor-cell origin and did not have any graft rejection. The 5 patients who survived more than 3 months developed chronic graft-versus-host disease of the skin, but no other organs were affected.

Currently, bone marrow transplantation is a well-established treatment modality for children with relapsed cases of leukaemia or fatal metabolic diseases. However with the common nuclear family structure in Hong Kong, it is very difficult to find a sibling who is identically matched for human leukocyte antigen (HLA). On the other hand, unrelated bone marrow donor transplants require very strict HLA compatibility with the recipient, because severe graft-versus-host disease is one of the major causes of transplantation-related mortality. With a cord blood bank, the cord blood donated from the public can be stored and used in an unrelated umbilical cord blood transplantation, when a sibling who is HLA-compatible with the patient is not available.

 
Ischaemic stroke care in Hong Kong

Hong Kong Med J 2004;10:124-129

The Hong Kong Neurological Society and the Hong Kong Stroke Society issued a consensus statement to provide guidelines for all health care professionals who are involved in the care of acute stoke. The statement was published in the April 2004 issue of Hong Kong Medical Journal.

The consensus statement focuses on the care of ischaemic stroke, which is responsible for more than 70% of the local incidence of stroke. Because stroke is a heterogenous condition, the care of each patient should be tailored to individual�s needs. It was indicated that the major components of stroke care included organisation of the stroke services, acute assessment, acute treatment, and secondary prevention.

Researchers indicated in the consensus statement that, quality of stroke care can be improved by setting up of a geographically designated acute stroke unit, creation of an effective multidisciplinary team, re-organisation of health delivery system to facilitate patient-oriented service, training of staff, and collaboration among various specialties and the community health system.

In 2001, there were 3130 deaths from stroke, accounting for 9.4% of all deaths in Hong Kong.

 

 

The Hong Kong Medical Journal is a continuation of the former Journal of the Hong Kong Medical Association.
The Hong Kong Medical Journal is published by the Hong Kong Academy of Medicine and the Hong Kong Medical Association.
Copyright © 1995-2008 HKAM. All rights reserved.
URL: http://www.hkmj.org
Layout, design, and revisions Copyright © 2008 HKAM.
Revised 7 Aug 2008