Hong Kong Med J 1999;5:291-3 | Number 3, September 1999
Use of intravenous immunoglobulin in a patient with refractory myasthenia gravis associated with malignant thymoma
KK Lau, WC Ho
Department of Medicine, Princess Margaret Hospital, Princess Margaret Hospital Road, Kwai Chung, Hong Kong
We report on a case of refractory myasthenia gravis that was managed by using intravenous immunoglobulin. A 35-year-old Chinese woman with malignant thymoma-associated myasthenia gravis was treated by total thymectomy, followed by chemotherapy. Thirty months later, she developed respiratory failure and required mechanical ventilation for 2 months. A course of intravenous immunoglobulin was given and her condition improved significantly. Two weeks later, the patient became ambulatory, was prescribed oral pyridostigmine, and was discharged home.
Key words: Immunoglobulins, intravenous/therapeutic use; Myasthenia gravis/therapy; Thymoma/surgery
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