A three-year review of treatment of cervical intraepithelial neoplasia with large loop excision of the transformation zone

KS Chan, CW Kwok, KM Yu, SY Sin, LCH Tang
Department of Obstetrics and Gynaecology, Kwong Wah Hospital, Waterloo Road, Kowloon, Hong Kong

One hundred and eighty-five patients were treated with large loop excision of the transformation zone for cervical intraepithelial neoplasia from October 1992 through September 1994. All patients were followed up regularly until September 1995 to review the outcome and morbidity. Cure rates of 97.2% in the first six months and 95.4% at the end of the first 12 months were obtained. Thirteen patients (7.0%) were admitted as emergency cases for post-operative haemorrhage, which required suturing, cauterisation with silver nitrate or electrocoagulation, vaginal douching, or antibiotic treatment. One patient developed cervical stenosis and incomplete excisions were noted in 46 (24.9%) patients. Eleven (6.0%) patients had cervical carcinomas detected. Our findings further confirm that this method is a reliable and safe way to treat cervical intraepithelial neoplasia with an acceptable rate of morbidity.

Hong Kong Med J 1997;3:21-6

Key words: Cervix dysplasia; Cervical intraepithelial neoplasia; Cervix neoplasms; Surgery, gynecologic