Hong Kong Med J 2012;18:346–7 | Number 4, August 2012
An unusual cause for rings in the brain
Anulekha M John, Natarajan Vasanthi, Abhishek Khurana, Geeta Chacko, Promila Mohanraj, Vedantam Rajshekhar, Nihal Thomas
Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India
We report the case of a 35-year-old man from North India who presented with generalised tonic-clonic seizures and was found to have ring-enhancing brain lesions. He had a coincident adrenal mass lesion. Cultures from both regions grew Histoplasma capsulatum. He improved on treatment with itraconazole. This case is being reported since cerebral ring-enhancing lesions are rarely associated with histoplasmosis, and coincident adrenal involvement is also a rarity in an immunocompetent individual.
Key word: Histoplasmosis
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